Tuesday, April 26, 2011

Why Does Alexis Texas Black

His defenses against their bones

Iván Arriaga have ankylosing spondylitis. After years of hardship, he found the right medicine, which combines gentle exercise .- Carlos Rosillo


spondylitis occurs when lymphocytes attack the joints of the hip - Two out of every thousand people have varying degrees CARMEN
disease GIRONA - Madrid - 26/04/2011


Iván Arriaga, a Madrid 34, ankylosing spondylitis, an autoimmune disease that primarily affects the joints that connect the sacrum to hip. So it is very debilitating, painful produces stiffness and the person may end up unable to move .


"One day, playing football gave me a pain in the hip that took my breath away. Since 2000 I was diagnosed with the disease until 2004 that I started with some new drugs, took drugs and lived many moments of crisis because pain did not disappear, and not let me sleep, "he said. "I'm happy. The trick, in addition to medication, is exercise without sudden movements," he says.

The use of stem cells is emerging as a treatment option
spondylitis belongs to a group of rheumatic diseases affect two in every 1,000 people , although no studies, including one in Berlin, which increased to two in 100. Of these, 60% suffered from spondylitis. Its origin is unknown, and is manifested by inflammation, swelling and stiffness.

As happened to Ivan, ankylosing spondylitis appears at younger ages, between 18 and 30 years and, unlike other autoimmune diseases such as lupus, affects more men than women . Biologic therapies that block alpha-antiTNF molecule present in the cascade of inflammation, are most effective. In more advanced cases, inflammation generates chronic bone growth, complete fusion, and immobilization of the joint. Is what, in the case of the vertebrae, known as bamboo spine.

"It was thought that new bone is formed after inflammation or concomitantly, but there is now evidence that they are two separate but coupled processes and, probably, there are other mechanisms involved," said Eduardo Collantes, head Service of Rheumatology, Hospital Reina Sofía de Córdoba.

The International Society of Experts in spondyloarthropathies (ASAS its acronym in English) has developed new diagnostic criteria Still for clinical trials for early detection. The result is that you can identify a 15% increase in patients.

Eugenio de Miguel, La Paz Hospital in Madrid, is one of the few experts in the world that uses ultrasound for this purpose. " spondyloarthropathies are difficult to diagnose early . In 2005 we started doing ultrasound in the tissue that connects the tendon and bone in patients with two years of disease progression. Now we have found that provides a ratio of probability to predict the disease similar to that of resonance, "he says.

But progress does not stop there. There are high hopes stem cells. "These cells or their derivatives may be potential drugs for a wide fork diseases such as arthropathy, have as common denominator inflammation," says Francisco Vizoso , head of research unit Jove Hospital of Asturias Foundation. Something that remains to be tested.
published today in the country.

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